The knight in the big world of American TV series

Chapter 2338



Chapter 2338

Chapter 2338

In fact, it wasn't just death that was watching Thanos; even Eternity was watching him.

Death has a certain elegance; she's picky about those she favors. Those who worship or despise death rarely attract her attention. Simply put, she's the typical bitch. Whether you despise her or value her, she won't care much. Only those who inadvertently find transcendence or struggle in the face of death will capture her attention.

For example, Thanos.

Take Deadpool, for example!

That's right, Death is on Deadpool's side, something very few people know, not even Deadpool himself!

As we all know, Deadpool's creation actually stemmed from a conspiracy that turned out to be a series of coincidences!

Deadpool is just a cynical urban mercenary, the kind who takes any job, not exactly glamorous. He even does jobs like helping kids with their homework. His life has always been a mess, living for the moment, until he meets Vanessa, a stripper, and falls in love with her!

Only then did he begin to truly desire change.

Then, dramatically, he was diagnosed with cancer.

In order to continue his relationship with Vanessa, he resolutely joined an experimental treatment program... Similar programs exist all over the world, and they are generally experimental treatments that explore different approaches. The effectiveness of these treatments is usually entirely dependent on luck! But there is one advantage: these experimental treatments are generally free!

This perfectly suits the needs of a poor guy like Deadpool, who is in the late stages of cancer and has no money, so he has no choice but to take a gamble.

Unfortunately, he was unlucky.

This is a derivative project based on Colonel Stryker's work on mutants... Stryker's death at Kay's hands does not mean that the US government has completely given up on research about mutants. In fact, the US government has never given up on this research, but it has become more covert and no longer targets mutants.

They targeted ordinary people.

Stryker's research revealed that there is no clear boundary between mutants and humans. Mutants can mate to create ordinary humans, and ordinary humans can mate to create mutants. There is no reproductive isolation between them. What does this mean? It means that they are actually the same kind of beings.

Even the claim that mutants are a form of human evolution is incorrect.

The two are not related by evolution, but rather by some kind of recessive mutation.

In science fiction movies, we often witness scenes where doctors or scientists inject animals with a drug, causing their genes to mutate and evolve into a terrifying new species. These mutated creatures possess extraordinary strength and even turn against humans, plunging the world into chaos and unrest. However, this is merely a fictional plot in science fiction. In real life, while mutant animals or humans like those in movies are extremely rare, scientists have revealed through in-depth research that each person carries more than 60 gene mutations. From this perspective, each of us can be considered a unique "mutant." Scientists have discovered that in addition to the genes inherited from both parents, each person carries fifty to sixty gene mutations that are not present in their parents. These mutations are not acquired through inheritance but rather arise from mutation. This discovery overturns traditional understanding, as it was previously believed that children's gene mutations mainly came from their parents. However, new research shows that this phenomenon of gene mutation is prevalent in everyone, and the mutated genes carried by individuals are often not present in either parent. To delve deeper into the roots of human gene mutations, scientists conducted a detailed analysis of every gene in a group of young children. The results showed that almost every child carried over 6000 potential mutated genes. Whether these genes will eventually mutate is primarily influenced by the child's future lifestyle and environment. Furthermore, this study revealed a startling discovery: in children, up to 92% of mutated genes initially originated from the father, while only 36% came from the mother. This finding indicates that in most families, the primary source of gene mutations in children is paternal inheritance.

Why do individuals carry numerous mutated genes yet rarely exhibit significant physiological changes? Scientists explain that it's not that changes don't occur, but rather that these changes are often subtle. Typically, gene mutations in the human body are associated with disease, but not all mutations have adverse effects; some gene mutations may even promote an individual's superior development.

Therefore, mutants and normal people are actually no different; the only difference is the genetic mutation that causes them to appear distinct, but fundamentally, they are the same. Due to practical needs, the US government cannot directly research mutants… at least not in the way of things like Stryker's approach of using mutants as resources!

But the US government took a different approach; they planned to use genetic mutation technology to turn ordinary people into mutants!

In the vast river of life, the continuation and development of every species are inseparable from the subtle regulation of genes. Gene mutation, as a key phenomenon in this regulatory process, is not only an important source of biodiversity, but also a crucial window for humankind to understand the mysteries of life and explore the root causes of diseases.

Gene mutation, simply put, is a sudden change in the gene sequence. This change can occur at any location on the DNA, ranging from the substitution, insertion, or deletion of a single base pair to the duplication, inversion, or translocation of a larger segment. These seemingly minor changes can trigger a chain reaction, affecting gene expression and function, and consequently significantly impacting the organism's phenotype. Gene mutation is a ubiquitous phenomenon in nature, beyond the control of the organism; it can occur spontaneously or be induced by external factors such as radiation or chemicals. Neither bacteria, plants, nor humans can completely avoid gene mutation. The effects of gene mutation on organisms are complex and diverse. On the one hand, it can endow organisms with new traits, increase biodiversity, and drive species evolution; on the other hand, it can also lead to diseases, such as hereditary diseases and cancer. Therefore, research on gene mutation not only helps us understand the nature of life but also provides important clues for disease prevention and treatment.

In nature, gene mutations are random. Radiation, chemicals, and even "mistakes" in cell replication can trigger these "tiny spelling errors." Most of these mutations are harmless, but some can lead to disease risks, such as cancer. Interestingly, some mutations have given humans "extraordinary adaptability." For example, the Tibetan people of the Lhasa Plateau can live freely at an altitude of 4000 meters without experiencing altitude sickness. The secret lies in their EPAS1 gene. Compared to people living in the plains, the EPAS1 gene in Tibetans has undergone a "key spelling change," preventing an excessive increase in red blood cells in their blood, thus avoiding altitude sickness. This "life-changing base mutation" is actually a product of "natural selection." For thousands of years, humans living in high-altitude environments have continuously "selected" for advantageous gene mutations, and ultimately, individuals with "high-altitude survival advantages" have been preserved. The same principle applies to some populations in Africa. While sickle cell anemia is a disease, it has "stubbornly persisted" in certain parts of Africa. Why? It turns out that while this mutation leads to abnormal red blood cell morphology, it is precisely this change in morphology that makes it more difficult for malaria parasites to infect these deformed red blood cells. In other words, this "genetic error" becomes a "survival tool" in an environment where malaria is prevalent. If the Tibetan people's adaptation to the high altitude is a "lucky genetic mutation," then cancer is a "catastrophic genetic mutation." The essence of cancer is a "spelling error" in DNA—when the "brake genes" or "accelerator genes" that control cell growth mutate, the cell may lose control and begin to divide wildly, eventually forming a tumor.

A typical example is the "p53 gene mutation". p53 is a "tumor suppressor gene" in the human body. Under normal circumstances, it can monitor the "health status" of cells. Once it detects DNA damage, it will repair it and even command the cell to "commit suicide" to prevent cancer.

However, if a base in the p53 gene is altered, the original "protective mechanism" will fail, allowing cancer cells to grow uncontrollably. Research has found that benzo[a]pyrene, a chemical carcinogen found in smoking, binds to DNA, causing the "G" at position 157 of the p53 gene to change to a "T," one of the high-risk mutations leading to lung cancer. A small "G to T" change can turn the "guardian of the cell" into an "out-of-control sentinel."

In the past, humans were almost "helpless" in the face of gene mutations. If DNA was damaged or misspelled, they could only accept "fate's arrangement."

But now, scientists have found the "key to gene repair"—DNA repair enzymes. These enzymes act like "proofreaders," detecting "spelling errors" during DNA replication and attempting to correct them. However, the DNA repair "proofreading mechanism" is not perfect; the older one gets, the lower the repair efficiency, especially in environments with high reactive oxygen species (ROS), where DNA damage occurs much faster than repair, contributing to aging and cancer. Is it possible to enhance DNA repair capabilities? Research has found that some small molecules may help repair DNA, such as PQQ (pyrroloquinoline quinone) and ergothioneine. PQQ, known as "mitochondrial growth factor," promotes mitochondrial proliferation and reduces ROS attacks in cells; while ergothioneine is a powerful "antioxidant molecule" that protects DNA from ROS attacks, reducing spelling errors. Even more excitingly, the advent of CRISPR gene-editing technology makes it possible for humans to "actively repair" spelling errors in DNA. Scientists are using the CRISPR system, which acts like "precise molecular scissors," to cut out "wrong bases" and replace them with "correct letters," opening up new avenues for treating genetic diseases and cancer.

A single base change could lead to the evolution of high-altitude adaptations in humans, or it could trigger cancer. A tiny "spelling error" can drastically alter a person's destiny. However, destiny is not necessarily unchangeable. With the advancement of gene repair technology and DNA repair enzymes, humanity may one day gain control over the "editing rights of gene spelling," and even be able to "revise" the book of destiny for each individual.

The US government wants to use these technologies to create mutants.

The so-called medical experiment project that Deadpool sought help from was a similar project team.

It was actually a scam... but those people didn't completely fool Deadpool!

Deadpool joined the Weapon X program. During the program's execution, his body was injected with Wolverine's genes, and he endured inhuman torture in extremely harsh environments. It was these hardships that forged the unkillable Deadpool. His suffering was not in vain; instead, it endowed him with power surpassing Wolverine's, making him truly immortal.

In the process, Death noticed Deadpool!

Honestly, there are many people struggling on the brink of death, so Deadpool isn't surprising!

But Deadpool's attitude toward death makes death feel comfortable.

The core reason Death is attracted to Deadpool lies in his cynical, humorous personality and his unique attitude towards death, which she finds novel and appealing. Deadpool is known for breaking the fourth wall, self-deprecating humor, and incessant chatter—qualities that stand out in a serious universe. As an abstract entity, Death typically deals with fearful or pessimistic souls, and Deadpool's easygoing attitude fascinates and delights her. Deadpool has faced death multiple times due to his immortality, yet he neither fears death nor resists fate, instead dealing with it with amusement. This nonchalance resonates with Death's essence, fueling her interest.

Interestingly, Deadpool and Death have actually communicated.

And more than once.

While Deadpool was being tortured, he saw a beautiful woman with an amazing figure appear in front of him and talk to him more than once in his hazy vision.

He thought it was Vanessa.

Deadpool and Vanessa... they're practically a match made in heaven.

The two are very compatible in many ways.

So Deadpool started dating that woman... a hazy, brief, but passionate romance.

Death is intrigued by this… No one truly loves death. Not even the most fervent believers in death; their worship of death stems primarily from fear of it. No one truly loves death.

But Deadpool is different; this guy really dares to do it!


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